Lou Davis is searching for their sister Violetta Head. The last she was heard from she was living in Nashville, Tennessee. Violetta had three children, Sammy, Bell, and Mary. Lou is her youngest sibling.
A later ad was taken out by a Mrs. Loui Davis in December of 1886 searching for a sister by the same name. It's likely that Lou and Loui are the same woman, short for Louisa. That ad may be found here: https://informationwanted.org/items/show/2148
Lou also took out two other ads searching for her friends Irvin Loveless, found here: https://informationwanted.org/items/show/2572, and Lethea Winters, found here: https://informationwanted.org/items/show/2573
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